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2015;138:e355

Beta-3 adrenergic receptors can desensitise under chronic agonist exposure, a phenomenon documented in the context of other beta-adrenergic agonists

Conversely, medications that further slow gastric emptying, such as anticholinergics or opioid analgesics, may exacerbate gastrointestinal adverse effects including nausea, vomiting, and constipation

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Keep a comprehensive symptom log tracking headaches alongside other variables: injection timing, food intake, fluid consumption, sleep quality, stress levels, and menstrual cycle (if applicable)